Posted by neuropathology blog 6 hours 50 minutes ago.
Dentatorubral-pallidoluysian atrophy is an autosomal dominant spinocerebellar ataxia which occurs most frequently among the Japanese. "Dentato" refers to the dentate nucleus of the cerebellum; and "rubral" alludes to the red nucleus. "Pallido" of course i...
Posted by neuropathology blog 2 days 13 minutes ago.
On more than one occasion, I have been discussing something with a colleague and remembered that I had blogged about that very same issue some months previously. Then, in order to find the post, I would have to try to remember when I posted on the subjec...
Posted by neuropathology blog 4 days 8 hours ago.
According to Prof. Jeff Lichtman (pictured) of Harvard's Center for Brain Science, the data storage capacity of the human brain is 1 million petabytes. A petabyte is equal to 1000 terabytes; and a terabyte is equal to 1000 gigabytes. In other words, the h...
Posted by neuropathology blog 6 days 3 hours ago.
Remak cells, named after Polish-born Robert Remak (1815-1865)(pictured), are Schwann cells which do not myelinate, but rather surround unmyelinated peripheral nerve fibers. According to Greenfield's Neuropathology (8th Edition), "unmyelinated axons are al...
Posted by neuropathology blog 1 week 3 days ago.
Central core disease is a congenital myopathy defined by the presence on muscle biopsy microscopy of numerous muscle fibers that lack oxidative activity, thus making "cores" on NADH-stained slides within muscle fibers. Reported to be one of the most frequ...
Posted by neuropathology blog 2 weeks 2 hours ago.
The American Cancer Society recently put out a publication entitled Cancer Facts and Figures 2008 in which it is reported that there will be 21,810 new brain and other nervous system cancers in the United States in 2008. Compare that to the estimated numb...
Posted by neuropathology blog 2 weeks 3 days ago.
We had an interesting case here last week of a 48-year-old gentleman with a clinical diagnosis of exacerbation of "some kind of an autoimmune encephalitis". The clinicians were wondering about CNS vasculitis and multiple sclerosis but really didn't know w...
Posted by neuropathology blog 3 weeks 2 hours ago.
On Wednesday, I wrote about the fact that the brains of gorillas weigh only about 40% as much as human brains. There is, however, one way in which our brains are similar to simians: the presence of the von Economo neuron.Constantin von Economo demonstrat...
Posted by neuropathology blog 3 weeks 3 hours ago.
I just heard that Kevin Roth, MD, director of neuropathology at the University of Alabama, has been named chair of the UAB Department of Pathology. Congratulations, Dr. Roth!
Posted by neuropathology blog 3 weeks 2 days ago.
"The average adult brain weight of a human is 1300-1400 g; an adult gorilla's brain weighs only 500 g." - From Dan Brat's introductory chapter in Prayson's Neuropathology (2005). By the way, I heard from an inside source that Prayson has agreed with the p...
Posted by neuropathology blog 3 weeks 3 days ago.
I just heard on National Public Radio that conservative columnist Robert Novak, about whom I wrote last week when it was announced that he had a brain tumor, will no longer be working for the Chicago Sun-Times. When you hear the word "dire" on a news stor...
Posted by neuropathology blog 4 weeks 7 hours ago.
And now for another in my occasional Best of the Month series, where I march through the past months choosing only the very best blog posts. This one, which features the illustrious Dr. Mark Cohen (pictured) is from Thursday, April 10, 2008: The esteeme...
Posted by neuropathology blog 1 month ago.
Long-awaited results of a Phase III trial of tarenflurbil (Flurizan) have failed to achieve statistical significance on either of its two primary endpoints (cognition and activities of daily living). The company developing the drug, Myriad Genetics, is ab...
Posted by neuropathology blog 1 month ago.
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Posted by neuropathology blog 1 month ago.
Conservative political columnist Robert Novak has a brain tumor, although the lesion has yet to be biopsied for diagnosis. According to an article in the on-line New York Times, "Last week, while driving in Washington, Mr. Novak struck a pedestrian, who w...
Posted by neuropathology blog 1 month ago.
This is a high-power picture of the interthalamic adhesion of an 81-year-old man with a clinical diagnosis of Dementia with Lewy Bodies. Again, see the collection of neuron cell bodies along with glial cells. I should remind you that not everyone has an i...
Posted by neuropathology blog 1 month ago.
I must revise a post from May 19, 2008 in which I quoted Dr. George R. Leichnetz, neuroanatomist at Virginia Commonwealth University and author of Digital Neuroanatomy: An Interactive CD Atlas with Text (Wiley-Liss, 2006). At that time, Dr. Leichnetz emai...
Posted by neuropathology blog 1 month ago.
Here's an article describing today's passing of Estelle Getty, 'The Golden Girls' actress.
Posted by neuropathology blog 1 month ago.
All of these are recent common searches on Yahoo. To see the complete list, go to:http://buzzlog.buzz.yahoo.com/overall
Posted by neuropathology blog 1 month ago.
The esteemed Dr. Doug Shevlin fowarded me this New York Times article about another guy with an M.D. after his name who blogs. Dr. Arnold Kim, pictured above, writes MacRumors.com, which monitors new developments coming out of the notoriously secretive Ap...
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